MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded by a short open reading frame within mitochondrial 12S rRNA. Research suggests that cellular stress and exercise can influence MOTS-C biology and that the peptide can interact with metabolic stress-response pathways, including folate-purine metabolism, AICAR accumulation, AMPK signaling, and adaptive nuclear gene expression. Most efficacy evidence remains preclinical, and no FDA-approved MOTS-C drug has been established.
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Mitochondrial Research Compound
10 mg · Purity Exceeds 99% · For Research Only
A mitochondrial-derived peptide for laboratory research into AMPK signaling, mitochondrial-nuclear pathway characterization, and exercise-physiology signaling models. Designed for in-vitro and animal-model studies involving metabolic pathway analysis, NRF2-associated antioxidant signaling, and mitokine biology research.
$200.00
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Research identityMOTS-C; mitochondrial ORF of the 12S rRNA type-c peptideSequence length16 amino-acid residuesCommon sequenceMRWQEMGYIFYPRKLRApprox. molecular mass~2,174.6 DaCompound classMitochondrial-derived peptidePhysical formLyophilized research material; confirm presentationAnalytical controlsIdentity, purity, net content, oxidation/degradation profile, and residual solvents
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Quick answers to common questions.
Still have a question? It is encoded by a short open reading frame within mitochondrial 12S rRNA
MRWQEMGYIFYPRKLR.
Metabolic stress signaling, including AICAR/AMPK-related mechanisms and adaptive gene expression.
The field is active but much of the functional evidence is preclinical.
No FDA-approved MOTS-C drug has been established.
All VESPR products are sold for research use only. They are not intended for human consumption, therapeutic, or diagnostic use. Our peptides are designed exclusively for controlled laboratory research, educational studies, or analytical testing. Every product label and supporting document clearly reflects this compliance standard.
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Choose Your Vials For laboratory and research use only. Not for human consumption.